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Nearly every American adult has a health condition that could lead to heart failure, yet nine out of 10 have never even heard of it. Now, the American Heart Association (AHA) is sounding the alarm on cardiovascular-kidney-metabolic (CKM) syndrome, a newly defined cluster of interconnected diseases that doctors have been treating separately for decades.
The condition encompasses a cluster of interconnected conditions—including heart disease, kidney disease, diabetes, and obesity—that often occur together, significantly increasing the risk of heart attack, stroke, and heart failure. It was first defined in a 2023 AHA Presidential Advisory. Despite affecting roughly 90 percent of U.S. adults, few people have heard of it, according to a recent AHA survey.

