Breakthrough Packaging Cuts Mercury in Canned Tuna by 35%

Chalmers University of Technology
8 Min Read
Breakthrough Packaging Cuts Mercury in Canned Tuna by 35%
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Pouring Liquid Amino Acid Cysteine Into a Jar of Canned Tuna
In the image, you can see one of the researchers pouring the liquid amino acid cysteine into a jar of canned tuna. The study showed that this novel ‘active packaging’ technique removed up to 35 percent of the accumulated mercury in canned tuna, significantly reducing human exposure to mercury via food. Credit: Chalmers University of Technology/Hanna Magnusson

Scientists created a packaging solution that reduces mercury in canned tuna by up to 35%, making fish consumption safer.

Fish is an excellent source of high-quality protein, rich in omega-3 fatty acids and other essential nutrients. However, some fish, particularly tuna, are prone to accumulating toxic mercury, making their consumption a health concern.

Researchers from research-intensive university located in Gothenburg, Sweden that was founded in 1829 following a donation by William Chalmers, a director of the Swedish East India Company. It focuses on technology, science, architecture, and shipping.

” data-gt-translate-attributes=”[{“attribute”:”data-cmtooltip”, “format”:”html”}]” tabindex=”0″ role=”link”>Chalmers University of Technology in Sweden have developed an innovative method to reduce mercury levels in canned tuna. By packaging the tuna in a water-based solution containing the amino acid cysteine, they were able to remove up to 35% of the accumulated mercury, significantly lowering human exposure to this toxic element.

While fish and other seafood provide essential nutrients, they can also expose consumers to methylmercury, the most hazardous form of mercury. This toxic compound binds to proteins in fish tissue and accumulates in species higher up the food chain, such as tuna, posing potential health risks.

Przemyslaw Strachowski and Mehdi Abdollahi
Chalmers researchers Przemyslaw Strachowski and Mehdi Abdollahi work with samples in the lab. Credit: Chalmers University of Technology/Hanna Magnusson

Packaging solution draws out the mercury

According to the World Health Organisation (WHO), mercury is one of the ten most harmful chemicals for humans. Exposure can damage the central nervous system, with fetuses and young children being particularly sensitive to the effects. That is why dietary recommendations for pregnant women advise caution with tuna consumption.

Mehdi Abdollahi
Mehdi Abdollahi, Associate Professor at the Department of Life Sciences, Chalmers University of Technology, Sweden. Credit: Chalmers University of Technology/Anna-Lena Lundqvist

Our study shows that there are alternative approaches to addressing mercury contamination in tuna, rather than just limiting consumption. Our goal is to improve food safety and contribute to enhanced human health, as well as to better utilize food that is currently under certain restrictions,” says Mehdi Abdollahi, Associate Professor at the Department of Life Sciences at Chalmers and coordinator of a project called Detoxpak.

The concept of so-called active packaging is to develop materials, for example, a liquid inside a can, that interact with food during storage − for instance, to increase the shelf life. However, this concept has never previously been used to improve food safety.

In a previous study, the researchers investigated the possibility of coating packages with thiolated silica to capture mercury from canned fish. What they observed, was that the forces binding the mercury within the tuna tissue prevented it from being released.

Proteins in tuna tissues, particularly sulfur-containing

Amino acids are a set of organic compounds used to build proteins. There are about 500 naturally occurring known amino acids, though only 20 appear in the genetic code. Proteins consist of one or more chains of amino acids called polypeptides. The sequence of the amino acid chain causes the polypeptide to fold into a shape that is biologically active. The amino acid sequences of proteins are encoded in the genes. Nine proteinogenic amino acids are called “essential” for humans because they cannot be produced from other compounds by the human body and so must be taken in as food.

” data-gt-translate-attributes=”[{“attribute”:”data-cmtooltip”, “format”:”html”}]” tabindex=”0″ role=”link”>amino acids, strongly bind and accumulate mercury due to the strong interactions involving thiol groups from these amino acids.

A jar of tuna flakes
A jar of tuna flakes, stands next to a pot containing the active packaging solution – the liquid amino acid cysteine. Credit: Chalmers University of Technology/Hanna Magnusson

“By knowing that, we decided to add one of them, cysteine, to a water solution in which fish meat can be immersed. We believed this would allow some of the mercury to be drawn out and instead bind to the solution and be discarded. Further research is needed to take care of the removed mercury,” says Przemysław Strachowski, first author, and at the time of study, a postdoc at the Department of Life Sciences at Chalmers.

Przemyslaw Strachowski
Przemyslaw Strachowski, former Postdoctoral Researcher at the Department of Life Sciences, Chalmers University of Technology, Sweden. Chalmers University of Technology/Per Svanström

Up to 35 percent of mercury removed

In the study, the researchers discovered that the greater the surface area of fish flesh in contact with the cysteine solution, the higher the mercury uptake. The highest value of mercury reduction, 35 percent, was reached when testing canned minced tuna, from regular grocery stores. They also discovered a maximum threshold of two weeks, after which no further changes occurred.

In the current study, however, the researchers did not observe any noticeable changes in the appearance or smell of the tested fish samples. Cell-based assays have also proven the safety of the developed technology.

“The beauty of this type of packaging is that it is active while the product is on the shelf. No additional production steps would be needed if a method like this were used industrially. The application of our results could increase the safety margin for fish consumption,” says Przemysław Strachowski.

More about the method:

  • In the study, fish protein extracts in the form of dry powder, fresh and lab-steamed fish in fillet and mince forms, and commercially available samples of canned tuna, both in larger pieces and as minced fish, were used.
  • No extra additives, like pH modifiers, were needed for this process. Only the cysteine concentration was adjusted in the water. Increasing cysteine levels improved mercury removal, but only up to a certain point. A 1.2 percent concentration level was optimal.

Reference: “New Insight into Mercury Removal from Fish Meat Using a Single-Component Solution Containing cysteine” by Przemysław Strachowski, Geeta Mandava, Johan Lundqvist, Romain Bordes and Mehdi Abdollahi, 2 October 2024,
Global Challenges.
DOI: 10.1002/gch2.202400161

Funding: Svenska Forskningsrådet Formas

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